Updates from September, 2013 Toggle Comment Threads | Keyboard Shortcuts

  • kubke 15:12 on September 22, 2013 Permalink | Reply
    Tags: , , lifelong learning,   

    Spent a large proportion of the weekend setting up the github repos. I feel like an absolute idiot at times but if I use it enough I am sure that even *I* can get a hang of it. Since I signed up for two coursera classes to learn R, I figured github would be a good place to keep the notes. One step at a time

    • kubke 21:56 on September 25, 2013 Permalink | Reply

      well – turns out that the code of conduct from coursera says I cannot share test questions and answers – so github is no a choice. Dang.

  • kubke 16:21 on September 9, 2013 Permalink | Reply
    Tags: , ,   

    Almost 2 hours meeting with studentC. I can see the shift in the discussion from the “intellectual” to the “executive”. There is still a lot of domain language I need to learn. #morereadingtodo

  • kubke 12:44 on September 4, 2013 Permalink | Reply
    Tags: , , manuscripts   


    • kubke 12:48 on September 4, 2013 Permalink | Reply

      Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds?

      Felipe S. Medina, Gavin R. Hunt1, Russell D. Gray, J. Martin Wild, M. Fabiana Kubke

      Glia have been implicated in a variety of functions in the central nervous system, including the control of the neuronal extracellular space, synaptic plasticity and transmission, development and adult neurogenesis. Perineuronal glia forming groups around neurons are associated with both normal and pathological nervous tissue. Recent studies have linked reduction in the number of perineuronal oligodendrocytes in the prefrontal cortex with human schizophrenia and other psychiatric disorders. Therefore, perineuronal glia may play a decisive role in homeostasis and normal activity of the human nervous system.

      Here we report on the discovery of novel cell clusters in the telencephala of five healthy Passeriforme, one Psittaciform and one Charadriiforme bird species, which we refer to as Perineuronal Glial Clusters (PGCs). The aim of this study is to describe the structure and distribution of the PGCs in a number of avian species.

      PGCs were identified with the use of standard histological procedures. Heterochromatin masses visible inside the nuclei of these satellite glia suggest that they may correspond to oligodendrocytes. PGCs were found in the brains of nine New Caledonian crows, two Japanese jungle crows, two Australian magpies, two Indian mynah, three zebra finches (all Passeriformes), one Southern lapwing (Charadriiformes) and one monk parakeet (Psittaciformes). Microscopic survey of the brain tissue suggests that the largest PGCs are located in the hyperpallium densocellulare and mesopallium. No clusters were found in brain sections from one Gruiform (purple swamphen), one Strigiform (barn owl), one Trochiliform (green-backed firecrown), one Falconiform (chimango caracara), one Columbiform (pigeon) and one Galliform (chick).

      Our observations suggest that PGCs in Aves are brain region- and taxon-specific and that the presence of perineuronal glia in healthy human brains and the similar PGCs in avian gray matter is the result of convergent evolution. The discovery of PGCs in the zebra finch is of great importance because this species has the potential to become a robust animal model in which to study the function of neuron-glia interactions in healthy and diseased adult brains.

  • kubke 22:44 on June 2, 2013 Permalink | Reply
    Tags: , , publication   

    what a week! Sent 3 manuscripts out, sent out the review for on PLOS ONE paper, did the Women in Leadership workshop, organised the content for 2 courses in 2014, submitted the paper on recommendations for Open Access publishing for the Faculty, submitted the animal ethics protocol, registered for eResearch Symposium and, oh, yes, renegotiated the terms of my mortgage. All and all a very productive week! And monday is a holiday – Yay!

  • kubke 09:05 on May 5, 2013 Permalink | Reply

    Ok, so moved my very small collection of Posterous files here – a bit of a change of focus, but so be it.

  • kubke 17:51 on April 18, 2013 Permalink | Reply
    Tags: ,   

    Dechorionated zebrafish embryos for about 2 hours today. There is a first time for almost everything. Thouse embryos are really cute!

  • kubke 13:39 on April 16, 2013 Permalink | Reply
    Tags: ,   

    So I took the plunge and am now on my way to get some zebrafish embryos. Have been in love with them since I came across them as a model for neuromuscular development as I was looking for a lab to do a PhD. Well, that is step 1. Let’s see what happens on Step 2.

  • kubke 09:01 on April 16, 2013 Permalink | Reply
    Tags: , , teaching   

    It sometimes seem that even after teaching is over, it never really is – oh well…..

  • kubke 09:43 on April 8, 2013 Permalink | Reply

    Argh! I am back!

  • kubke 09:38 on January 22, 2013 Permalink | Reply
    Tags: , ,   

    I’ll be happy to see the end of fixing those little buggers

  • kubke 10:52 on December 3, 2012 Permalink | Reply
    Tags: ,   

    Wow – only monday morning and my head is already ready to explode!

  • kubke 20:35 on November 22, 2012 Permalink | Reply  

    So apparently co-investigator is not sufficiently descriptive for my collaborator in the HRC grant. Wut?!

  • kubke 21:48 on November 17, 2012 Permalink | Reply  

    There are few things as satisfying as getting notice of a paper being sent in for review.

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